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Refoule
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PRODUCT FEATURE
"REFOULE" is the end product of the joint team research effort with:
a. Using the patented Komaki Extract (sutivumin complex) formulated, researched, analysed and developed by Prof. Dr. Hisatoki Komaki, Nobel Prize Nominee for Medicine and Physiology in 1975.
b. Using supreme strains of lactobacillus sporogenes known as LACRIS isolated by Dr Nakayama of Yamanashi University, and
c. Using proprietary formulation of catechin (camellia sinensis) in green tea researched by Dr. Hidetaka Ohno.
1. Unique and special patented "freeze-drying" process protects the microbes (lactic acid bacteria and yeast) organism from damage during manufacturing and storage
4. Each sachet product viability content is ensured up to at least 30 rigorous quality control tests during the manufacturing process.
7. All lactic acid bacteria and yeast exhibit excellent multiplication growth and rapid proliferation and adherence to intestine epithelial cells due to the presence of the Komaki Extract.
2. Special patented process of using Komaki Extract (sativumin complex) produces a highly effective cell rejuvenation of 16 types of lactic acid bacteria and 24 types of yeast. (The Patent Certificate No. is 3354889 registered with the Japan Patent Office on 27 Sept 2002.)
5. A definite cryoprotectant is added before freezing to prevent any damage to the lactic acid bacteria and the yeast.
8. Highly effective and clinically stable against moisture, light, heat and air with a specially designed natural stabilizer and a high grade sachet material. (The recommended storage temperature should not exceed 45 degree Celcius)
3. Patented proprietary formulation of green tea extract (catechin) with vitamins produces a highly effective odour elimination effect on bad breath, gas formation, and bowel waste. (This is due to joint research effort with Dr. Hidetaka Ohno)
6. All lactic acid bacteria and yeast are known to be resistant to known antibiotics like penicillin, streptomycin, aureomycin, etc.
9. All lactic acid bacteria and yeast are resistant to both gastric acids and bile salts due to the inclusion of Komaki Extract in the formulation.
PRODUCT BACKGROUND
Good Bacteria
ZENDAMA
40
Opportunistic Bacteria
HIYORIMI
30
Bad Bacteria
AKUDAMA
30
There are 100 types of intestinal bacteria in the 100 trillion intestinal bacteria inhabiting the intestine. Out of these, 40 types are categorized as Good Bacteria, 30 types as Bad Bacteria and 30 types as Opportunistic Bacteria.
If the number of bad bacteria such as clostridium perfringens and coliform bacteria increases, health will be affected. On the other hand, if good bacteria such as lactobacillus and yeast are dominant, then good health will prevail. It has been found that one of the factors contributing to the rise in chronic diseases throughout the world relates to the increased dominance of bad bacteria over good bacteria.
Many scholars and researchers have pointed out that when bad bacteria dominate the intestine; constipation is worsened causing foul stool odor or gas (ammonia, hydrogen sulfide, indole and scatole) release, and skin roughening before it negatively affects the entire bodily functions such as the kidney, digestive and circulatory functions.
In short, to remain healthy, the "second kidney" - the intestine - has to be dominated by good bacteria. To achieve that, the intestinal flora must be well maintained and cultured.
Having attained both the status and reputation as a successful entrepreneur, the late Konosuke Matsushita - founder of Matsushita Electric Works - embarked on his visionary search for ways that will improve human lifespan. While doing so, he came to know Dr. Hisatoki Komaki who was a foremost figure in the study of microbial cultivation. Konosuke Matsushita later invited him to be the Special Advisor for Matsushita Electric Works Head Office under a special Bio-Agricultural Research Center which was set up within the company to launch into his research work.
At the end of the research, they came to the conclusion that "making the intestine healthy and improving the function of intestinal bacteria" are the factors that would produce the best results. The ultimate fruit of this special project was the creation of a unique food supplementation with 16 types of supreme strains of lactic acid bacteria and 24 types of yeasts, with patented Komaki Extract and Green Tea Essence; marketed under the name of "REFOULE" in Japan.
Lactobacillus, a good bacterium, is the bacterium commonly known to improve the functioning of the intestinal flora. However, it is an acknowledged fact that lactobacillus in yogurts or lactobacillus - containing foods taken orally is broken down by the pH-low gastric acid and the bile acid in the duodenum even before it reaches the intestine. To overcome this issue, Dr. Komaki came up with the following ideas.
"In the intestine, the growth of the lactobacillus is prospered by the yeast secretion and the growth of the yeast is prospered by the lactobacillus secretion. In other words, these two microorganisms co-exist and co-prosper on their respective secretion. If this is true, then what matters most is not the live lactobacillus, or yeast but its respective biomass component or better known as secretion. As the secretions cannot be broken down by the secretions into the intestine."
Having conceived this idea, Dr. Komaki then symbiotically cultivated 40 types of good bacteria, namely lactobacillus and yeast, by feeding them with Sativumin Complex, an odorless nutrient of garlic. He let their secretions to ooze freely and made that secretion into a drink. This rejuvenated ingredient component that is included in "REFOULE" is the award-winning "L16Y24 - Komaki Concentrate (Lactobacillus-Yeast) Secretions *".
INGREDIENT COMPOSITION
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Isomal Oligosaccharide
-
Lactose
-
Lactosucrose Syrup
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Tehalose
-
Maltose
-
Komaki Extract / Dextrin
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Anhydrous Crystal Glucose
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Bacillus Coagulans
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Green Tea Extract / Essence
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Citric Acid
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Lemon Powder
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Natural Lemon Flavour
Bacillus Coagulans (Lacris)
Bacteria & Yeast Types
16 TYPES
STRETPCOCCUS
1. Thermophillus
2. Cremoris
3. Faecalis
4. Lactis
LACTOBACILLUS
5. Bulgaricus
6. Acidophilus
7. Casei
8. Delbruckii
9. Arabinosus
10. Caucasicus
11. Lactis
12. Leishmanni
13. Musicus
14. Thermophilus
15. Plantarum, and
LEUCONOSTOC
16. Mesenteroides
24 TYPES
SACCHAROMYCES
1. Cerevisae
2. Pastorianus
3. Intermedius
4. Validus
5. Ellipsoideus
6. Mali Risler
7. Mandschuricus
8. Vordermannii
9. Peka
10. Shasshing
11. Piriformis
12. Anamensis
13. Cartilaginosus
14. Awamori
15. Batatae
16. Coreanus
17. Robustus
18. Carlsbergensis
19. Monacensis
20. Marxianus
21. Lactis
22. Rouxii
ZYGOSACCHAROMYCES
23. Major and Hansenula
24. Anomala
Apart from the value-added and patented "L16Y24 - Komaki Concentrate Secretion", "REFOULE" also utilizes the particular strain of Bacillus Coagulans SANK 70258 (spore-forming lactic acid bacteria called LACRIS) derived from green wheat germ which are the "Lactobacillus Sporegenes". These spores which are isolated by Dr Nakayama exhibit superior thermal resistant, acid resistant and high stability properties will ensure the ingested lactic acid bacteria will survive the environment of stomach and duodenum, so that a sufficiently large number of them will reach the site of action intact to proliferate actively and endow with high lactic acid production.
"Lactobacillus Sporogenes" is also available as the component to improve the functionality of lactobacillus - yeast secretion. While it shares the same lactic acid secreting function like other various lactobacilli, it is different in certain areas. These differences include its capability to produce spores and its capability to withstand acid, heat, salt, and sugar in order to survive.
If lactobacillus sporogenes as spores are orally taken, the spores will germinate and secretes lactic acid in the intestine because it is able to withstand the strong acidity (pH 2) of the gastric acid to reach the intestine without being broken down. However, as lactobacillus sporogenes are not indigenous intestinal bacteria, it will be excreted in the stool after 7-10 days. Therefore, taking a consistent amount of lactobacillus sporogenes' spores daily is equivalent to having it as an intestinal inhabitant.
Another unique component for good intestinal flora is the catechin found in the blended component of "green tea extract and essence" which weakens the bad bacteria. Through its synergistic effect with the lactobacillus - yeast secretion, the intestinal environmental improvement is strengthened to eliminate bad body odor and foul breath for an improved grooming. At the same time, a comprehensive detox effect (detoxification and bowel cleansing) can be achieved by the addiction of citric acid, an organic acid that has intestinal regulation function to an intestinal environment where the blood pH is slightly alkalinized.
PROCESS FLOW FOR THE PRODUCTION OF LACTOBACILLUS-YEAST SECRETION IN REFOULE
